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To install PyMOL on Mac, you can drag PyMOL.app on the /Applications shortcut[^3^]. You can also use



The Educational-use-only PyMOL builds are provided "AS IS" with no obligation to grant download access, fix bugs, furnish updates, provide documentation, or meet any other need related to the educational-use PyMOL builds.


The PyMOL support team offers technical support, printed tutorials, and screencasts for commercial users. For those who prefer to learn from an expert instead, classroom-style training is available worldwide. PyMOL also has over 100,000 active users with community-sponsored support available on the popular PyMOLWiki and pymol-users email list.




Pymol Mac Download



  • Coot is the standard programfor model-building into density, written chiefly by Paul Emsley. Theextensions included with the PHENIX GUIallow control of Coot from PHENIX, including automatic loading of models andmaps. This requires a build of Coot that includes a working Pythoninterpreter; if the PHENIX extensions are not functioning, this is almostcertainly due to the lack of Python in the Coot build. Note: the installersavailable on the CCP4 web page have not worked with PHENIX in the past; asof May 2011, the Mac installer appears to be fine, but you will need to specifythe path (/Applications/coot.app) in the PHENIX preferences.For Linux:We recommend downloading installers directly fromPaulEmsley's web page. Any file with "python" in the name is suitable for usewith PHENIX. Most of these will work on other OSes than those named, but wehaven't tested them extensively.

  • For Mac:Two options are available: use the Finkpackage manager, or download a standalone installation. Both aredescribed on Bill Scott's web page. Note that you will need to berunning Snow Leopard (OS 10.6) to use many of these, but some obsolete (butstill functional) builds of Coot for older OSes are available. The builds arenow nightly, and include both command-line and graphical installers. For older versions ofMac OS (10.4 or 10.5), the more recent packages do not work with PHENIX, soyou will need to use the obsoleteCoot 0.6 build.

To run Coot from the PHENIX GUI, you will either need to have the 'coot'executable somewhere in your shell's searchpath, or enter it inPreferences->Graphics->Full path to Coot. A few specific paths are searchedautomatically. On Mac, most installations should be automatically detected,but you may need to set the path explicitly to ensure that the correct versionis used.


Several plugins are included, To add new plugins they need to be added to /Applications/PyMOLX11Hybrid.app/pymol/modules/pmgtk/startup/ To access this folder control-click on the PyMOLX11Hybrid application and select "Show Package Contents" from the dropdown menu and navigate to the desired folder. For example the LIQUID fuzzy pharmacophore model plugin is available here to install expand the archive and copy all file into /Applications/PyMOLX11Hybrid.app/pymol/modules/pmgtk/startup/Whilst many of the plugins work fine, you may need to amend some file paths, in this case in LIQUID_Plugin.pyChange


If you already have Python installed and wish to use PyMOL with that interpreter, the process is virtually identical. The only difference is that you need to download a version of PyMOL which matches your desired Python version in the filename. For example:


At the request of various Macintosh users, as well as Apple itself, we have created MacPyMOL, a special native Aqua version of PyMOL for the Macintosh. The latest version of MacPyMOL can be downloaded from


4. Compiling from source code -If you known enough about compiling C/C++ source code on macOS,you can download PyMol source code and build MyPol fromGitHub repository github.com/schrodinger/pymol-open-source.


All platforms: On first launch PyMOL will request a license file. Navigate to the location where you downloaded it and select it to enter the information. The license file expires annually and will need to be updated to ensure full functionality. The current expiration date is 2/11/22.


The Purdue Libraries provide a campus-wide license for ChemOffice Professional (which includes ChemDraw). This means anyone at Purdue, whether faculty, staff, or student, can legally download their own personal copy of ChemOffice Professional and install it on their machine, at work and at home. Here are the steps for downloading and installing the latest software:


Unpack (unzip) the downloaded file and follow the instructions to install (for Windows, simply double-click the ".msi" file). The installation will take a few minutes. Just use the default settings. When asked if you want to make PyMOL your default molecular viewer, just press "Yes". You should now be ready to go.


CAVER can be used in two possible ways. If you are accustomed with the PyMOL application, you can download the CAVER plugin for PyMOL. Then the standard functionality of PyMOL application for the subsequent exploration of computed channels can be used. The other possibility is to take advantage of our CAVER Analyst application, which has been designed exactly for the problem of detection and mainly for further exploration of channels. It includes the CAVER algorithm for computation of channels in static molecule as well as in molecular dynamics. So when you want to avoid the limited capabilities of PyMOL when operating with large sequences of dynamics simulations, CAVER Analyst is the right solution. CAVER Analyst can be downloaded and installed as a standalone version or you can use the online version based on the Java Web Start technology.


Columbia University Libraries is happy to announce the acquisition of a site license for the renowned Schrodinger suite of molecular modeling software. This download gives you access to the Small Molecule Drug Discovery suite, the Biologics suite, and the Materials Science suite.


I have pymol downloaded and in use on my mac. I open it from the applications folder. I can successfully run a python script in it. However, I cannot import any libraries within that script. The way I currently know to add importable libraries to a python environment is through anaconda navigator. Is there a way to get anaconda to see the pymol application as a environment that I could then add libraries to?


So if you want to use your script in PyMOL and install a library simply call the python within PyMOL, say /Applications/PyMOL.app/Contents/bin/python3.7 on a Mac. On a Linux you probably installed with conda install -c schrodinger pymol to not end up with 1.8 anyway, so this does not apply. On Windows, you will have to find where it is installed (import sys and print sys.executable in PyMOL).


So if you want to use PyMOL within your Python code conda install -c schrodinger pymol or compile it if pip. Yes, it's wasteful and you have to re-add the licence.About this mode, remember to run without the display pymol_argv = ['pymol', '-qc'] or __main__.pymol_argv = ['pymol', '-qc'].


Now that you know where the pymol's python3 exec is you can create a virtualenv based on it:virtualenv --python="/usr/bin/python3".In my case it happened to be /usr/bin/python but yours might be different.


For all other other users, Visio can be purchased directly from GovConnection.com or via our BuyWays System. Once the desired application is purchased, send the proof of purchase to ITServiceDesk@umb.edu. You will receive a link to download the application.


For all other other users, Project can be purchased directly from GovConnection.com or via our BuyWays System. Once the desired application is purchased, send the proof of purchase to ITServiceDesk@umb.edu. You will receive a link to download the application.


Contact Research Computing (it-rc@umb.edu) to request an activation code and download link. Note that we have limited licenses and may not be able to fulfill your request. Student licenses are available at here.


This adds a menu option under plugins "Install PyVOL." Clicking this and selecting install will download PyVOL and all its dependencies. On MacOS and Linux, this should be a complete installation. Windows currently requires independent installation of MSMS. PyVOL will be available to run once PyMOL is restarted.


Otherwise MSMS must be installed manually by downloading it from MGLTools and adding it to the path. PyMOL distributions from Schrodinger have MSMS included; however, it must still be added to the path manually. The executable is located at:


Avogadro can be downloaded for Windows, Mac OS X & Linux and should work on most other Unix systems which support the Qt package. At the moment, we do not support tablets, smartphones, etc. (i.e., iOS, Android, or Windows phone) but these are being considered for future releases.


Pymol 2.5.4 for Mac is free to download from our software library. The program is categorized as Design & Photo Tools. This Mac app was originally designed by Schrodinger. Our antivirus analysis shows that this Mac download is virus free. The file size of the latest installer available is 133 MB.


The Plugins, like APBS, Volume Ramp Editor, and the Molecular Builder are only available in the PyMOLX11Hybrid version of MacPyMOL. Please rename the downloaded "MacPyMOL.app" to "PyMOLX11Hybrid.app" to enable this functionality.


Packages named like pymol-v1.8.6.0-CentOS7-x86_64.tar.gz are tightly integrated with the system environment and allow small packages sizes due to fewer bundled dependencies. They typically require from the system:


Here you can download the latest version of the CCP4 Software Suite, version8.0, code name Addingham. See the announcementfor further information. See also theinstallation instructions for details on installing CCP4.


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Also note I encountered problems whencopying things to & from the Windows partition in WSL-1 (lost permissionsettings & was unable to chmod them back). If youstick to just working with the Linux variant of Edge & downloading to theLinux partition it all works ok. 2ff7e9595c


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